Every year, millions of “weight loss” dollars are spent by pharmaceutical companies in the search for a drug that can prevent and/or reverse obesity. And every year, billions of “weight loss” dollars are spent by consumers on supplements, gym memberships, pills, potions & lotions.
Unfortunately, every year…almost all of that money is wasted as obesity rates creep higher & higher…pushing up the number of people with type 2 diabetes, heart disease, metabolic syndrome, etc.
But what if instead of looking for a drug or a vitamin or a diet or a workout…the solution to obesity was genetic therapy?
- What if there was a way to reverse obesity, type 2 diabetes, etc thanks to a combination of leptin genes and a “safe” adeno-associated virus delivered to you via an IV injection?
- What if researchers were already working on this?
- What if the research has already seen success in lab mice studies?
Would that get you excited about a scientific cure for obesity & it’s related lifestyle diseases?
Assuming you answered yes to the above question, I will continue with a brief overview of the science for all you weight-loss geeks.
A Very Brief Overview of the Science
- Researchers use adeno-associated viruses as a vehicle to deliver leptin into your body
- The virus/leptin combo is injected into test subjects (mice) via an IV
- The nonpathogenic virus infects the host’s cells with the leptin gene
- The expression of the leptin gene is played out over a long period of time
- Unlike a direct injection of leptin into the host’s brain, the adenovirus delivery method circumvents the “normal” leptin resistance feedback loop
Allowing for a sustained drop in appetite, a sustained drop in food consumption, a sustained drop in body-fat, reduced blood sugar levels, reduced triglyceride levels, improved glucose tolerance, etc, etc, etc…
What does this mean to YOU?
Unfortunately not very much right now. All of this research is being conducted on mice…meaning that you shouldn’t expect to get an anti-obesity injection from your doctor anytime soon.
Still, as a health & fitness nerd, this science is pretty darn cool. If you think so too, pass it on.
Public interest via social media, means more attention via mainstream media, which means an increased chance that someone / some company with deep pockets will fund additional research.
And additional research can’t help but speed up the process and maybe, just maybe…we’ll have a safe & effective treatment for obesity & it’s related diseases.
And that is pretty darn cool too.
- Regulatory Peptides
- Molecular Therapy
- Pediatric Research
- Gene Therapy
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