Back in May of this year, I told you about Tesofensine, a new diet drug being developed by the Danish drug company, NeuroSearch. Well, it’s back in the news.

A new study, published in the online version of the Lancet, is singing the praises of Big Pharma’s latest attempt at weight loss in a pill.

Following up on their initial tests, this latest study claims that “Tesofensine produces a weight loss of approximately 10 percent more than placebo and diet in obese patients,” said lead researcher Dr. Arne Astrup, from the Department of Human Nutrition, Faculty of Life Sciences, at the University of Copenhagen.

Other drugs produce only about 5 percent weight loss, Astrup noted.

The researchers seem to be pretty excited about tesofensine’s ability to compete head to head with gastric bypass surgery for the title of medical weight loss champion.

According to the researchers, “This drug could replace the need for gastric bypass surgery in some obese patients”.

“There is an enormous gap between the existing weight-loss compounds and gastric surgery,” Astrup said. “Tesofensine could close that gap.

“If you combine the drug with an effective diet, you could probably reach the 20 percent weight loss seen in gastric surgery.”

This is my favorite part of the quote:

“Tesofensine could compete with gastric surgery and be offered to those who are below the threshold for surgery or for patients who do not wish [to have] gastric surgery,” Astrup said.

“There are also patients who cannot tolerate gastric surgery.”

So let me get this straight.

Finally, there is a solution for all of those poor unfortunate overweight individuals who happen to be below the threshold for gastric surgery, cannot tolerate surgery or foolishly do not wish to have gastric surgery.

And that solution is:


Perhaps there is another solution.

How about a little less of this:

And a little more of this:

Instead of:

Relying on a pharmaceutical solution which:

  • Alters levels of three key brain chemicals – serotonin, dopamine and noradrenaline

Professor Steve O’Rahilly, a Cambridge University obesity expert, said: ‘If we could treat obesity, like we treat high blood pressure, with safe, effective and affordable drugs this would be an enormous boon to health care.

‘To date, obesity drugs that have been effective have not been safe, and conversely those that are safer, are relatively ineffective. The results with this new drug demonstrate that, over a six-month period, it is quite effective.

However, as the drug is likely to have actions on parts of the brain not involved in weight control, the risk of serious side effects on longer-term administration will need to be watched very carefully.’

  • Stops working as soon as you stop taking it.

Once starting the drug, people would need to keep taking it to maintain the benefit, Astrup said. “There is no treatment that is working beyond its taking. This is true for all anti-diabetic medication, hypertension medication and everything, including anti-obesity drugs,” he said. “It’s a long-term treatment, and, in some cases, a permanent treatment to keep body weight down.

  • And has numerous short-term side effects:
  • Nausea
  • Diarrhea
  • Constipation
  • Insomnia
  • Mood changes, such as anger and confusion
  • Increased Heart Rate
  • Increased Blood Pressure

The choice is yours.